ARCO Consensus on the Pathogenesis of Non-traumatic Osteonecrosis of the Femoral Head

Quanjun Cui, Woo Lam Jo, Kyung Hoi Koo, Edward Y. Cheng, Wolf Drescher, Stuart B. Goodman, Yong Chan Ha, Phillippe Hernigou, Lynne C. Jones, Shin Yoon Kim, Kyu Sang Lee, Mel S. Lee, Yun Jong Lee, Michael A. Mont, Nobuhiko Sugano, John Taliaferro, Takuaki Yamamoto, Dewei Zhao

Research output: Contribution to journalArticlepeer-review


Osteonecrosis of the femoral head (ONFH) is a devastating disease frequently leading to femoral head collapse and hip arthritis. Specifically, non-traumatic ONFH primarily affects young and middle-aged adults. Although compromised local circulation of the femoral head seems to be pathognomonic for the disease, the pathogenesis is perplexing and continues to be an area of scrutiny and research. Comprehension of the pathogenesis is of crucial importance for developing and guiding treatments for the disease. Therefore, we provide an up-to-date consensus on the pathogenesis of non-traumatic ONFH.

Original languageEnglish (US)
Pages (from-to)1-15
Number of pages15
JournalJournal of Korean Medical Science
Issue number10
StatePublished - Mar 15 2021

Bibliographical note

Publisher Copyright:
© 2021 The Korean Academy of Medical Sciences.


  • Osteonecrosis
  • Osteonecrosis of the Femoral Head
  • Pathogenesis

PubMed: MeSH publication types

  • Journal Article
  • Review


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