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Ar-variant–positive CTC: A surrogate for a surrogate for taxane therapy outcome?

Research output: Contribution to journalArticlepeer-review

Abstract

Circulating tumor cells' (CTC) biomarkers may become indicators for selection of therapy. The presence of androgen receptor (AR)-variant-positive CTCs may be markers indicating the need for switching therapy. Methods for AR-variant mRNA isolation from CTCs and confirmation of expression are critical factors needed for these techniques to be clinically applicable.See related article by Tagawa et al., p. 1880.

Original languageEnglish (US)
Pages (from-to)1696-1698
Number of pages3
JournalClinical Cancer Research
Volume25
Issue number6
DOIs
StatePublished - 2019

Bibliographical note

Publisher Copyright:
© 2018 American Association for Cancer Research.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Humans
  • Male
  • Neoplastic Cells, Circulating
  • Prostatic Neoplasms, Castration-Resistant
  • RNA, Messenger
  • Receptors, Androgen
  • Taxoids

PubMed: MeSH publication types

  • Comment
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Journal Article
  • Research Support, N.I.H., Extramural

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