Approach to Persistent Microscopic Hematuria in Children

Mahmoud Kallash, Michelle N. Rheault

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Persistent isolated microscopic hematuria is relatively common in pediatric practice, affecting around 0.25% of children. Isolated microscopic hematuria can be caused by a myriad of potentially benign or serious causes, including urologic issues; kidney stones; glomerular diseases, including disorders of the glomerular basement membrane; hematologic abnormalities; and others. The challenge for the pediatrician or pediatric nephrologist is to distinguish children with potentially progressive forms of kidney disease versus other causes while minimizing cost and inconvenience for the child and family. This manuscript will review the multiple potential causes of microscopic hematuria and provide a framework for the initial evaluation and monitoring of such patients.

Original languageEnglish (US)
Pages (from-to)1014-1020
Number of pages7
Issue number9
StatePublished - Sep 1 2020

Bibliographical note

Funding Information:
Dr. Michelle N. Rheault receives research funding from Advicenne, Genentech, Reata, Retrophin, and Sanofi, outside the submitted work. Author Contributions

Publisher Copyright:
Copyright © 2020 by the American Society of Nephrology.


  • Alport syndrome
  • IgA nephropathy
  • IgA vasculitis
  • glomerular and tubulointerstitial diseases
  • hematuria
  • hypercalciuria
  • pediatric nephrology


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