Applications of Stereotactic Radiosurgery in Neuro-Oncology

Kunal S. Patel; Paul H. Chapman; Marc Bussiere; Jay S. Loeffler; Clark C. Chen

doi:10.1016/B978-0-12-800945-1.00026-4

Applications of Stereotactic Radiosurgery in Neuro-Oncology

Kunal S. Patel
, Paul H. Chapman
, Marc Bussiere
, Jay S. Loeffler
, Clark C. Chen

Neurosurgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Radiosurgery involves the focal administration of conformal ionizing radiation (IR) to a diseased tissue. The conformal nature of the radiation delivered limits injury to surrounding nontarget tissue. The therapeutic window of IR is based on the observation that tumor cells harbor a decreased DNA repair capacity relative to nonneoplastic cells. Therefore, radiosurgery is an important treatment option in neuro-oncology. The foundations, imaging, and applications of radiosurgery in neuro-oncology are discussed in this chapter.

Original language	English (US)
Title of host publication	Handbook of Neuro-Oncology Neuroimaging
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	257-271
Number of pages	15
ISBN (Electronic)	9780128011683
ISBN (Print)	9780128009451
DOIs	https://doi.org/10.1016/B978-0-12-800945-1.00026-4
State	Published - Apr 12 2016

Keywords

Acoustic neuromas
Cerebral metastases
CyberKnife
Gamma Knife
Gliomas
LINAC
Meningiomas
Pituitary adenomas
Radiosurgery
Radiotherapy

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10.1016/B978-0-12-800945-1.00026-4

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title = "Applications of Stereotactic Radiosurgery in Neuro-Oncology",

abstract = "Radiosurgery involves the focal administration of conformal ionizing radiation (IR) to a diseased tissue. The conformal nature of the radiation delivered limits injury to surrounding nontarget tissue. The therapeutic window of IR is based on the observation that tumor cells harbor a decreased DNA repair capacity relative to nonneoplastic cells. Therefore, radiosurgery is an important treatment option in neuro-oncology. The foundations, imaging, and applications of radiosurgery in neuro-oncology are discussed in this chapter.",

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AU - Patel, Kunal S.

AU - Chapman, Paul H.

AU - Bussiere, Marc

AU - Loeffler, Jay S.

AU - Chen, Clark C.

PY - 2016/4/12

Y1 - 2016/4/12

N2 - Radiosurgery involves the focal administration of conformal ionizing radiation (IR) to a diseased tissue. The conformal nature of the radiation delivered limits injury to surrounding nontarget tissue. The therapeutic window of IR is based on the observation that tumor cells harbor a decreased DNA repair capacity relative to nonneoplastic cells. Therefore, radiosurgery is an important treatment option in neuro-oncology. The foundations, imaging, and applications of radiosurgery in neuro-oncology are discussed in this chapter.

AB - Radiosurgery involves the focal administration of conformal ionizing radiation (IR) to a diseased tissue. The conformal nature of the radiation delivered limits injury to surrounding nontarget tissue. The therapeutic window of IR is based on the observation that tumor cells harbor a decreased DNA repair capacity relative to nonneoplastic cells. Therefore, radiosurgery is an important treatment option in neuro-oncology. The foundations, imaging, and applications of radiosurgery in neuro-oncology are discussed in this chapter.

KW - Acoustic neuromas

KW - Cerebral metastases

KW - CyberKnife

KW - Gamma Knife

KW - Gliomas

KW - LINAC

KW - Meningiomas

KW - Pituitary adenomas

KW - Radiosurgery

KW - Radiotherapy

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UR - https://www.scopus.com/pages/publications/84978342494#tab=citedBy

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DO - 10.1016/B978-0-12-800945-1.00026-4

M3 - Chapter

AN - SCOPUS:84978342494

SN - 9780128009451

SP - 257

EP - 271

BT - Handbook of Neuro-Oncology Neuroimaging

PB - Elsevier Inc.

ER -

Applications of Stereotactic Radiosurgery in Neuro-Oncology

Abstract

Keywords

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