Applications of Stereotactic Radiosurgery in Neuro-Oncology

Kunal S. Patel, Paul H. Chapman, Marc Bussiere, Jay S. Loeffler, Clark C. Chen

Research output: Chapter in Book/Report/Conference proceedingChapter


Radiosurgery involves the focal administration of conformal ionizing radiation (IR) to a diseased tissue. The conformal nature of the radiation delivered limits injury to surrounding nontarget tissue. The therapeutic window of IR is based on the observation that tumor cells harbor a decreased DNA repair capacity relative to nonneoplastic cells. Therefore, radiosurgery is an important treatment option in neuro-oncology. The foundations, imaging, and applications of radiosurgery in neuro-oncology are discussed in this chapter.

Original languageEnglish (US)
Title of host publicationHandbook of Neuro-Oncology Neuroimaging
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Number of pages15
ISBN (Electronic)9780128011683
ISBN (Print)9780128009451
StatePublished - Apr 12 2016


  • Acoustic neuromas
  • Cerebral metastases
  • CyberKnife
  • Gamma Knife
  • Gliomas
  • Meningiomas
  • Pituitary adenomas
  • Radiosurgery
  • Radiotherapy


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