Abstract
A fundamental problem in developmental biology concerns the proportioning of the developing tissue of a morphallactic system into different cell types in a way that is independent of the overall size of the tissue. The two main models for positional, information in pattern formation, the source-sink models and the Turing reaction-diffusion models, have shortcomings that limit their applicability. In a previous paper, we described a model that can produce perfectly scale-invariant spatial patterns and analyzed some of its mathematical properties. In the present paper, we demonstrate some of the shortcomings of the standard reaction-diffusion models and discuss the applicability of our model to developmental systems.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Differentiation |
| Volume | 28 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1984 |
Bibliographical note
Funding Information:Acknowlegements. This work was supported in part by an NIH grant (no. 29123).