Response surface methodology (RSM) was utilized to optimize extraction conditions for the acetylcholinesterase inhibitor from Rhodiola sachalinensis. Optimized values for AChE inhibition and extraction yield were 19.41 and 13.35%, respectively, and these were in good agreement with the experimental values from validation, suggesting that RSM is a useful tool.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of the Korean Society for Applied Biological Chemistry|
|State||Published - Dec 3 2014|
Bibliographical notePublisher Copyright:
© 2014, The Korean Society for Applied Biological Chemistry.
- Alzheimer’s disease
- Rhodiola sachalinensis
- response surface methodology