Application of nonphosphorylative metabolism as an alternative for utilization of lignocellulosic biomass

Maria K. McClintock, Jilong Wang, Kechun Zhang

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations

Abstract

Production of chemicals via fermentation has been evolving over the past 30 years in search of economically viable systems. Thus far, there have been few industrially relevant chemicals that have seen commercialization, examples being lactic acid and ethanol. Currently, many of these fermentation processes still compete with food sources. In order to reduce this competition fermentation of alternative feedstocks, such as lignocellulosic biomass must to be utilized. Hemicellulosic sugars can be employed effectively for the production of chemicals by incorporating nonphosphorylative metabolism. This review covers nonphosphorylative metabolism, the pathways and enzymes involved, as well as the products that have been produced using nonphosphorylative metabolism.

Original languageEnglish (US)
Article number2310
JournalFrontiers in Microbiology
Volume8
Issue numberNOV
DOIs
StatePublished - Nov 23 2017

Bibliographical note

Funding Information:
This work was supported by a grant from the National Science Foundation through the Center for Sustainable Polymers (grant CHE-1413862).

Keywords

  • Biochemicals
  • Lignocellulose
  • Metabolic Engineering
  • Nonphosphorylative metabolism
  • Pathway design

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