Anxiety disorders and risk of self-reported ulcer

A 10-year longitudinal study among US adults

Farah Taha, Joshua D. Lipsitz, Sandro Galea, Ryan T. Demmer, Nicholas J. Talley, Renee D. Goodwin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: Previous epidemiologic studies have documented a link between anxiety disorders and ulcer among adults. Few studies have examined these associations over time and little is understood about the pathways underlying these relationships. Method: Data were drawn from n= 2101 adult participants in the Midlife Development in the United States I and II. Data on ulcer diagnoses were collected through self-report: among participants in the current sample, 38 reported ulcer at Waves 1 and 2 (prevalent ulcer), and 18 reported ulcer at Wave 2 but not at Wave 1 (incident ulcer). Panic attacks and generalized anxiety disorder at Wave 1 (1994) were examined in relation to prevalent (past 12 months) and incident ulcer approximately 10 years later at Wave 2 (2005). Results: Anxiety disorders at Wave 1 were associated with increased prevalence of ulcer [odds ratio (OR)=4.1, 95% confidence interval (CI)=2.0-8.4], increased risk of incident ulcer at Wave 2 (OR=4.1, 95% CI=1.4-11.7) and increased risk of treated ulcer at Wave 2 (OR=4.7, 95% CI=2.3-9.9) compared with those without anxiety. Conclusions: In this large population sample of adults, anxiety disorders were associated with an increased risk of ulcer over a 10-year period. These relationships do not appear to be explained by confounding or mediation by a wide range of factors. Future studies should address potential mechanisms underlying the relationship between anxiety and ulcer.

Original languageEnglish (US)
Pages (from-to)674-679
Number of pages6
JournalGeneral Hospital Psychiatry
Volume36
Issue number6
DOIs
StatePublished - Nov 1 2014
Externally publishedYes

Fingerprint

antineoplaston A10
Anxiety Disorders
Ulcer
Longitudinal Studies
Odds Ratio
Confidence Intervals
Anxiety
Panic Disorder
Self Report
Epidemiologic Studies

Keywords

  • Anxiety disorder
  • Epidemiology
  • Generalized anxiety disorder
  • Panic attack
  • Ulcer

Cite this

Anxiety disorders and risk of self-reported ulcer : A 10-year longitudinal study among US adults. / Taha, Farah; Lipsitz, Joshua D.; Galea, Sandro; Demmer, Ryan T.; Talley, Nicholas J.; Goodwin, Renee D.

In: General Hospital Psychiatry, Vol. 36, No. 6, 01.11.2014, p. 674-679.

Research output: Contribution to journalArticle

Taha, Farah ; Lipsitz, Joshua D. ; Galea, Sandro ; Demmer, Ryan T. ; Talley, Nicholas J. ; Goodwin, Renee D. / Anxiety disorders and risk of self-reported ulcer : A 10-year longitudinal study among US adults. In: General Hospital Psychiatry. 2014 ; Vol. 36, No. 6. pp. 674-679.
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