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Keyphrases
Antitumor Activity
100%
EGFR mutation
100%
Gefitinib
100%
Protein Level
100%
Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor (EGFR-TKI)
100%
Human Lung Cancer Cell Line
100%
Iressa
100%
Gene Copy number
100%
Epidermal Growth Factor Receptor Protein
100%
ZD1839
100%
Non-small Cell Lung Cancer (NSCLC)
33%
Epidermal Growth Factor Receptor
33%
Epidermal Growth Factor Receptor Gene
25%
Western Blotting
16%
Cancer Cell Lines
16%
In Vivo Effects
16%
Signaling Molecules
16%
Non-small Cell Lung Cancer Patients
16%
Phosphorylated Epidermal Growth Factor Receptor
16%
Epidermal Growth Factor Receptor Expression
16%
Clinical Trials
8%
Therapeutic Target
8%
Erlotinib
8%
Human Epidermal Growth Factor Receptor 2 (HER2)
8%
Molecular Markers
8%
Small Molecules
8%
Immunohistochemistry
8%
Response Marker
8%
Molecular Effects
8%
Cellular Effects
8%
Cancer Xenograft
8%
Growth Inhibition
8%
Downstream Signaling
8%
Surface Expression
8%
Flow Cytometry
8%
Fluorescence in Situ Hybridization
8%
Cell Cycle Arrest
8%
Athymic nude Mice
8%
Fluorescence-activated Cell Sorting
8%
Mutational Status
8%
In Vitro Effect
8%
Objective Response
8%
Receptor Tyrosine Kinase Inhibitor
8%
Epidermal Growth Factor Receptor Inhibitors
8%
Signaling Events
8%
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide Assay
8%
Resistant Cell Lines
8%
Lung-other
8%
Sensitive Lines
8%
Medicine and Dentistry
Non Small Cell Lung Cancer
100%
Receptor Protein
100%
Antineoplastic Activity
100%
Lung Cancer Cell Line
100%
Epidermal Growth Factor Receptor
100%
Epidermal Growth Factor Receptor Kinase Inhibitor
100%
Gefitinib
100%
Gene Dosage
100%
Receptor Gene
25%
Cell Cycle
12%
Receptor Expression
12%
Western Blot
12%
Clinical Trial
6%
In Vitro
6%
Cancer
6%
Erlotinib
6%
Cell Surface
6%
Fluorescence in Situ Hybridization
6%
Protein Tyrosine Kinase
6%
Immunohistochemistry
6%
Flow Cytometry
6%
Cell Cycle Arrest
6%
Gene Mutation
6%
Fluorescence Activated Cell Sorting
6%
Tumor Xenograft
6%
Tyrosine-Kinase Inhibitor
6%
Cell Cycle Checkpoint
6%
MTT Assay
6%
Signaling Protein
6%
Resistant Cell Line
6%
Molecular Marker
6%
Biochemistry, Genetics and Molecular Biology
Gene Dosage
100%
Cancer Cell
100%
Antineoplastic Activity
100%
Gefitinib
100%
Receptor Tyrosine Kinase Inhibitors
100%
Epidermal Growth Factor Receptor
100%
Receptor Gene
22%
Western Blot
11%
Cell Cycle
11%
Flow Cytometry
11%
Small Molecule
5%
Clinical Trial
5%
Genetic Marker
5%
Wild Type
5%
Signaling Protein
5%
Gene Mutation
5%
Erlotinib
5%
Cell Cycle Arrest
5%
Fluorescence in Situ Hybridization
5%
Cell Cycle Checkpoint
5%
Nude Mouse
5%
MTT Assay
5%
Pharmacology, Toxicology and Pharmaceutical Science
Antitumor Activity
100%
Receptor Protein
100%
Non Small Cell Lung Cancer
100%
Gefitinib
100%
Epidermal Growth Factor Receptor Kinase Inhibitor
100%
Epidermal Growth Factor Receptor
100%
Western Blot
12%
Clinical Trial
6%
Flow Cytometry
6%
Nude Mouse
6%
Fluorescence Activated Cell Sorting
6%
Protein Tyrosine Kinase Inhibitor
6%
Protein Tyrosine Kinase
6%
3 (4,5 Dimethyl 2 Thiazolyl) 2,5 Diphenyltetrazolium Bromide
6%
Erlotinib
6%
Molecular Marker
6%