In this study we demonstrate that hexahydrocolupulone (HHC) more effectively inhibits the growth in vitro of Gram-positive organisms than Mycobacterium tuberculosis or Escherichia coli. Vancomycin-resistant Enterococcus faecium, methicillin-resistant Staphylococcus aureus, and coagulase-negative staphylococci were inhibited by HHC at concentrations ≤ 4.06 mg/L. Growth inhibition profiles varied according to the microorganism evaluated (static for S. aureus and bactericidal for Bacillus subtilis).
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Antimicrobial Chemotherapy|
|State||Published - Oct 1998|