Antihistamines block radiation-induced taste aversions

Carolyn J. Levy; Marilyn E. Carroll; James C. Smith; Kurt G. Hofer

doi:10.1126/science.186.4168.1044

Antihistamines block radiation-induced taste aversions

Carolyn J. Levy
, Marilyn E. Carroll
, James C. Smith
, Kurt G. Hofer

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.

Original language	English (US)
Pages (from-to)	1044-1045
Number of pages	2
Journal	Science
Volume	186
Issue number	4168
DOIs	https://doi.org/10.1126/science.186.4168.1044
State	Published - 1974
Externally published	Yes

Publisher link

10.1126/science.186.4168.1044

Find It

Find It at U of M Libraries

Cite this

@article{fe9a4925e2914cdc88c34e6ef99abba7,

title = "Antihistamines block radiation-induced taste aversions",

abstract = "When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.",

author = "Levy, \{Carolyn J.\} and Carroll, \{Marilyn E.\} and Smith, \{James C.\} and Hofer, \{Kurt G.\}",

year = "1974",

doi = "10.1126/science.186.4168.1044",

language = "English (US)",

volume = "186",

pages = "1044--1045",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4168",

}

TY - JOUR

T1 - Antihistamines block radiation-induced taste aversions

AU - Levy, Carolyn J.

AU - Carroll, Marilyn E.

AU - Smith, James C.

AU - Hofer, Kurt G.

PY - 1974

Y1 - 1974

N2 - When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.

AB - When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.

UR - https://www.scopus.com/pages/publications/0016226866

UR - https://www.scopus.com/pages/publications/0016226866#tab=citedBy

U2 - 10.1126/science.186.4168.1044

DO - 10.1126/science.186.4168.1044

M3 - Article

C2 - 4143379

AN - SCOPUS:0016226866

SN - 0036-8075

VL - 186

SP - 1044

EP - 1045

JO - Science

JF - Science

IS - 4168

ER -

Antihistamines block radiation-induced taste aversions

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this