Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4

Elizabeth R. Kearney, Theresa L. Walunas, Robert W. Karr, Phillip A. Morton, Dennis Y. Loh, Jeffrey A. Bluestone, Marc Jenkins

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Immunology and Microbiology