This paper presents a simple and robust antifouling sensor based on a nano-wrinkle electrode with bovine serum albumin for electrochemically detecting small molecules in complex body fluids. The nano-wrinkle was prepared by a one-step shrinking technique, being capable of excluding large proteins in physical structures and enhancing the response of small molecules. The prepared sensor demonstrates excellent antifouling capability under discontinuous or continuous exposure to proteins or fetal calf serum, which preserves 97% of its original signal after a 21-day exposure to fetal calf serum and enabled the quantification of dopamine in the protein-coexisted environment with a low limit of detection (LOD) (1.09 μM) and a wide detection range from 20 to 1105 μM.
|Original language||English (US)|
|Title of host publication||2023 IEEE 36th International Conference on Micro Electro Mechanical Systems, MEMS 2023|
|Publisher||Institute of Electrical and Electronics Engineers Inc.|
|Number of pages||4|
|State||Published - 2023|
|Event||36th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2023 - Munich, Germany|
Duration: Jan 15 2023 → Jan 19 2023
|Name||2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS)|
|Conference||36th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2023|
|Period||1/15/23 → 1/19/23|
Bibliographical noteFunding Information:
This work was supported by the Science and Technology Development Plan of Jilin Province (20210204108YY).
© 2023 IEEE.
- Electrochemical sensor
- Shrinking technique