Antiepileptic drug therapy. Fine tuning the dosage regimen

T. E. Welty, N. M. Graves, J. C. Cloyd

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The first article in this series, published last month, acquainted readers with the basic principles of therapeutic drug monitoring and emphasized the value of this simple procedure in helping physician and patient reach their goal of optimal drug therapy. This month's article begins the analysis of specific therapeutic classes of drugs with a look at the antiepileptics. Because of some unique characteristics of these drugs and of epilepsy itself, fine tuning of the dosage regimen on the basis of concentrations of the drug in serum is crucial to achieving seizure control without toxicity. Dr Welty and associates discuss therapeutic ranges, side effects, and drug interactions of four major antiepileptics and present a detailed therapeutic plan for each.

Original languageEnglish (US)
Pages (from-to)287-305
Number of pages19
JournalPostgraduate Medicine
Volume74
Issue number5
DOIs
StatePublished - Jan 1 1983

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Anticonvulsants
Drug Therapy
Pharmaceutical Preparations
Drug Monitoring
Drug-Related Side Effects and Adverse Reactions
Drug Interactions
Epilepsy
Seizures
Therapeutics
Physicians
Serum

Cite this

Antiepileptic drug therapy. Fine tuning the dosage regimen. / Welty, T. E.; Graves, N. M.; Cloyd, J. C.

In: Postgraduate Medicine, Vol. 74, No. 5, 01.01.1983, p. 287-305.

Research output: Contribution to journalArticle

Welty, T. E. ; Graves, N. M. ; Cloyd, J. C. / Antiepileptic drug therapy. Fine tuning the dosage regimen. In: Postgraduate Medicine. 1983 ; Vol. 74, No. 5. pp. 287-305.
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