Anticytoplasmic antibodies in antinuclear antibody-negative lupus erythematosus. Correlation with clinical course

Mark S. Paller, W. Scott Moore, Eng Tan, Robert W. Schrier

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A patient with clinical manifestations of systemic lupus erythematosus (SLE) and without antinuclear antibodies was found to have anticytoplasmic antibodies. These anticytoplasmic antibodies were directed against ribosomal ribonucleoprotein, and the titer of anticytoplasmic and anti-ribosomal ribonucleoprotein antibodies correlated with the clinical course of the patient's illness. The importance of detecting anticytoplasmic antibodies and their role in producing disease in patients with SLE is discussed.

Original languageEnglish (US)
Pages (from-to)529-533
Number of pages5
JournalThe American Journal of Medicine
Volume75
Issue number3
DOIs
StatePublished - Sep 1983

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