Anticoagulation in adult patients supported with extracorporeal membrane oxygenation: guidance from the Scientific and Standardization Committees on Perioperative and Critical Care Haemostasis and Thrombosis of the International Society on Thrombosis and Haemostasis

Julie Helms, Corinne Frere, Thomas Thiele, Kenichi A. Tanaka, Matthew D. Neal, Marie E. Steiner, Jean M. Connors, Jerrold H. Levy

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Anticoagulation of patients supported by extracorporeal membrane oxygenation is challenging because of a high risk of both bleeding and thrombotic complications, and often empirical. Practice in anticoagulation management is therefore highly variable. The scope of this guidance document is to provide clinicians with practical advice on the choice of an anticoagulant agent, dosing, and the optimal anticoagulant monitoring strategy during extracorporeal membrane oxygenation support in adult patients.

Original languageEnglish (US)
Pages (from-to)373-396
Number of pages24
JournalJournal of Thrombosis and Haemostasis
Volume21
Issue number2
DOIs
StatePublished - Feb 2023

Bibliographical note

Funding Information:
MES has current research support from NIH grants and US Department of Defense contract. She has received honoraria for serving on advisory committee for Octapharma and receives NIH honoraria for serving on Infant Jarvik PumpKIN trial.

Funding Information:
MDN reports funding for research from the NIH, Department of Defense , Haemonetics, Instrumentation Laboratories, and Janssen Pharmaceuticals . He serves on the Scientific Advisory Board of Haima Therapeutics. He has received personal fees from Haemonetics, Janssen, and CSL Behring.

Funding Information:
KAT reports research funding from CellPhire, and served on the Scientific Advisory Board of Octapharma and HemoSonics .

Publisher Copyright:
© 2022 International Society on Thrombosis and Haemostasis

Keywords

  • anticoagulation
  • critical care
  • extracorporeal membrane oxygenation

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