TY - JOUR
T1 - Antibody response of pediatric solid organ transplant recipients to immunization against influenza virus
AU - Mauch, Teri Jo
AU - Crouch, Norman A.
AU - Freese, Deborah K.
AU - Braunlin, Elizabeth A.
AU - Dunn, David L.
AU - Kashtan, Clifford E.
N1 - Funding Information:
Supported by National Institute of Health Training Grant No. AM07087 (Dr. Mauch), by the Children's Kidney Disease Society, and by the Minnesota Department of Health.
PY - 1995/12
Y1 - 1995/12
N2 - We studied the immunogenicity of the 1992-1993 trivalent split-virus influenza vaccine in pediatric solid organ transplant recipients (PSOTRs) and their healthy siblings. One month after immunization, 41 (82%) of 50 subjects achieved protective titers of antibodies to influenza A, and 30 (60%) to influenza B, rates similar to those in healthy siblings. Achievement and persistence of protective titers occurred significantly more often in children with preexisting antibody. We recommend annual immunization of PSOTRs, their household contacts, and health care workers; immunologically naive PSOTRs may benefit from immunization before transplantation. (J PEDIATR 1995;127:957-60).
AB - We studied the immunogenicity of the 1992-1993 trivalent split-virus influenza vaccine in pediatric solid organ transplant recipients (PSOTRs) and their healthy siblings. One month after immunization, 41 (82%) of 50 subjects achieved protective titers of antibodies to influenza A, and 30 (60%) to influenza B, rates similar to those in healthy siblings. Achievement and persistence of protective titers occurred significantly more often in children with preexisting antibody. We recommend annual immunization of PSOTRs, their household contacts, and health care workers; immunologically naive PSOTRs may benefit from immunization before transplantation. (J PEDIATR 1995;127:957-60).
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U2 - 10.1016/S0022-3476(95)70037-4
DO - 10.1016/S0022-3476(95)70037-4
M3 - Article
C2 - 8523197
AN - SCOPUS:0029558176
SN - 0022-3476
VL - 127
SP - 957
EP - 960
JO - The Journal of pediatrics
JF - The Journal of pediatrics
IS - 6
ER -
