Ankara universitesi tip fakultesi hematoloji kliniginde yatan febril notropenik hastalarin aerob bakteriyel enfeksiyon etkenlerinin antibiyotik duyarliliklari

Infection is the main cause of mortality and morbidity in febrile neutropenic patients. In order to decrease the mortality and morbidity, empirical antibiotic therapy should be started as soon as possible in the beginning of fever. For this reason causative agents and their antibiotic susceptibility patterns must be routinely monitored. In this study, the antibiotic susceptibility patterns of pathogenic bacteria isolated from patients with febrile neutropenia were monitored for 2 years. The isolation rates of Gram negative and Gram positive bacteria from 118 patients as the causative agents of infections were 56% and 44% respectively. Susceptibility rates of enteric Gram negative and nonfermentative Gram negative bacilli against antibiotics which are commonly used for the empirical treatment in our hospital, were as follows respectively; 74% and 82% for seftazidime, 68% and 50% for sefotaxime, 91% and 67% for sefepim, 100% and 83% for imipenem, 84% and 67% for amikacin. There was no resistance to penicillin among pneumococci and beta haemolytic streptococci strains. Methicillin resistance was found to be 56% for staphylococci while all of them were found to be susceptible to vancomycin and teicoplanin.