Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus.

M. Rozenberg-Arska, G. T. Fabius, M. A. Beens-Dekkers, S. A. Duursma, L. D. Sabath, J. Verhoef

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

15 Staphylococcus aureus strains were isolated from 15 patients with staphylococcal bacteremia. Eight of these strains were shown to be tolerant for cloxacillin. Cloxacillin-tolerant strains were also tolerant for most of the cephalosporins tested except for cephapirin. Strains were not tolerant for clindamycin and gentamicin. Penicillin-tolerant staphylococci showed a high degree of synergism between gentamicin and cloxacillin or cephalothin and gentamicin.
Original languageUndefined/Unknown
Pages (from-to)352-355
Number of pages4
JournalChemotherapy
Volume25
Issue number6
StatePublished - 1979

Keywords

  • Anti-Bacterial Agents/pd [Pharmacology]
  • Cephalosporins/pd [Pharmacology]
  • Clindamycin/pd [Pharmacology]
  • Cloxacillin/pd [Pharmacology]
  • Drug Synergism
  • Gentamicins/pd [Pharmacology]
  • Microbial Sensitivity Tests
  • Penicillin Resistance
  • Penicillins/pd [Pharmacology]
  • Staphylococcus aureus/de [Drug Effects]

Cite this

Rozenberg-Arska, M., Fabius, G. T., Beens-Dekkers, M. A., Duursma, S. A., Sabath, L. D., & Verhoef, J. (1979). Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus. Chemotherapy, 25(6), 352-355.

Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus. / Rozenberg-Arska, M.; Fabius, G. T.; Beens-Dekkers, M. A.; Duursma, S. A.; Sabath, L. D.; Verhoef, J.

In: Chemotherapy, Vol. 25, No. 6, 1979, p. 352-355.

Research output: Contribution to journalArticle

Rozenberg-Arska, M, Fabius, GT, Beens-Dekkers, MA, Duursma, SA, Sabath, LD & Verhoef, J 1979, 'Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus.', Chemotherapy, vol. 25, no. 6, pp. 352-355.
Rozenberg-Arska M, Fabius GT, Beens-Dekkers MA, Duursma SA, Sabath LD, Verhoef J. Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus. Chemotherapy. 1979;25(6):352-355.
Rozenberg-Arska, M. ; Fabius, G. T. ; Beens-Dekkers, M. A. ; Duursma, S. A. ; Sabath, L. D. ; Verhoef, J. / Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus. In: Chemotherapy. 1979 ; Vol. 25, No. 6. pp. 352-355.
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T1 - Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus.

AU - Rozenberg-Arska, M.

AU - Fabius, G. T.

AU - Beens-Dekkers, M. A.

AU - Duursma, S. A.

AU - Sabath, L. D.

AU - Verhoef, J.

PY - 1979

Y1 - 1979

N2 - 15 Staphylococcus aureus strains were isolated from 15 patients with staphylococcal bacteremia. Eight of these strains were shown to be tolerant for cloxacillin. Cloxacillin-tolerant strains were also tolerant for most of the cephalosporins tested except for cephapirin. Strains were not tolerant for clindamycin and gentamicin. Penicillin-tolerant staphylococci showed a high degree of synergism between gentamicin and cloxacillin or cephalothin and gentamicin.

AB - 15 Staphylococcus aureus strains were isolated from 15 patients with staphylococcal bacteremia. Eight of these strains were shown to be tolerant for cloxacillin. Cloxacillin-tolerant strains were also tolerant for most of the cephalosporins tested except for cephapirin. Strains were not tolerant for clindamycin and gentamicin. Penicillin-tolerant staphylococci showed a high degree of synergism between gentamicin and cloxacillin or cephalothin and gentamicin.

KW - Anti-Bacterial Agents/pd [Pharmacology]

KW - Cephalosporins/pd [Pharmacology]

KW - Clindamycin/pd [Pharmacology]

KW - Cloxacillin/pd [Pharmacology]

KW - Drug Synergism

KW - Gentamicins/pd [Pharmacology]

KW - Microbial Sensitivity Tests

KW - Penicillin Resistance

KW - Penicillins/pd [Pharmacology]

KW - Staphylococcus aureus/de [Drug Effects]

M3 - Article

VL - 25

SP - 352

EP - 355

JO - Chemotherapy

JF - Chemotherapy

SN - 0009-3157

IS - 6

ER -