Antibiotic sensitivity and synergism of 'penicillin-tolerant' Staphylococcus aureus.

M. Rozenberg-Arska, G. T. Fabius, M. A. Beens-Dekkers, S. A. Duursma, L. D. Sabath, J. Verhoef

Research output: Contribution to journalArticlepeer-review

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Abstract

15 Staphylococcus aureus strains were isolated from 15 patients with staphylococcal bacteremia. Eight of these strains were shown to be tolerant for cloxacillin. Cloxacillin-tolerant strains were also tolerant for most of the cephalosporins tested except for cephapirin. Strains were not tolerant for clindamycin and gentamicin. Penicillin-tolerant staphylococci showed a high degree of synergism between gentamicin and cloxacillin or cephalothin and gentamicin.
Original languageUndefined/Unknown
Pages (from-to)352-355
Number of pages4
JournalChemotherapy
Volume25
Issue number6
StatePublished - 1979

Keywords

  • Anti-Bacterial Agents/pd [Pharmacology]
  • Cephalosporins/pd [Pharmacology]
  • Clindamycin/pd [Pharmacology]
  • Cloxacillin/pd [Pharmacology]
  • Drug Synergism
  • Gentamicins/pd [Pharmacology]
  • Microbial Sensitivity Tests
  • Penicillin Resistance
  • Penicillins/pd [Pharmacology]
  • Staphylococcus aureus/de [Drug Effects]

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