Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with adenocarcinoma of the gastroesophageal junction

J. D. Debes, S. M. Lagarde, E. Hulsenboom, P. A.E. Sillevis Smitt, F. J.W. Ten Kate, G. A. Sulter, J. J.B. Van Lanschot

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16 Scopus citations

Abstract

Anti-Yo-associated paraneoplastic cerebellar degeneration is a cancer-related syndrome affecting the nervous system. This syndrome occurs almost exclusively in middle-aged women with gynecological cancers and it is rarerly found in patients with other types of cancer or in males. In this report we describe a male patient adenocarcinoma of the gastroesophageal junction and PCD with anti-Yo antibodies. To our knowledge, this is only the third report of PCD with positive anti-Yo antibodies in an esophageal tumor and the first report in a tumor of the gastroesophageal junction.

Original languageEnglish (US)
Pages (from-to)395-397
Number of pages3
JournalDigestive Surgery
Volume24
Issue number5
DOIs
StatePublished - Oct 2007
Externally publishedYes

Keywords

  • Anti-Yo
  • Cerebellar degeneration
  • Esophageal cancer
  • Metastasis
  • Paraneoplastic syndrome

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