Abstract
Sch 29482 (SCH), a new broad-spectrum beta-lactam antibiotic, was studied in an in-vitro microtitre system using Mueller-Hinton broth for determining its antistaphylococcal activity. Each of the 68 isolates of staphylococci studied belonged to one of the following six groups, and had the median penem MIC values as noted in parentheses: penicillinase-positive (0.25 mg/l), or -negative (0.25 mg/l) Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (32 mg/l), or coagulase-negative staphylococci (128 mg/l), 'tolerant' Staph. aureus (0.012 mg/l), or methicillin-sensitive coagulase-negative staphylococci (
| Original language | Undefined/Unknown |
|---|---|
| Pages (from-to) | 189-194 |
| Number of pages | 6 |
| Journal | Journal of Antimicrobial Chemotherapy |
| Volume | 9 |
| Issue number | Suppl.C |
| State | Published - 1982 |
Keywords
- animal experiment
- drug comparison
- drug response
- drug sensitivity
- in vitro study
- Staphylococcus aureus
- 2 ethylthio 6 (1 hydroxyethyl)penem 3 carboxylic acid
- ampicillin
- cefalexin
- cefalotin
- cefamandole
- cephalosporin derivative
- meticillin
- nafcillin
- penem derivative
- penicillin derivative
- penicillin K