Anti-human immunodeficiency virus type 1 activities of U-90152 and U- 75875 in human brain cell cultures

P. K. Peterson, G. Gekker, S. Hu, C. C. Chao

Research output: Contribution to journalComment/debate

6 Scopus citations

Abstract

Antiviral activities of the reverse transcriptase inhibitors U-90152 and 3'-azido-2',3'-dideoxythymidine and the protease inhibitor U-75875 were compared in two culture models of human immunodeficiency virus type 1 brain infection. In a model involving acutely infected microglial cells, U-90152 was the most active, whereas in a model using chronically infected promonocytes, U-75875 was the most active.

Original languageEnglish (US)
Pages (from-to)2465-2468
Number of pages4
JournalAntimicrobial agents and chemotherapy
Volume38
Issue number10
DOIs
StatePublished - 1994

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