Anorexia of infection as a mechanism of host defense

M. J. Murray, A. B. Murray

Research output: Contribution to journalArticlepeer-review

200 Scopus citations

Abstract

The role of anorexia of infection as a mechanism of host defense was studied by force-feeding infected mice to a normal energy intake. Their mortality and survival times were then compared with those of infected mice feeding ad libitum. Mortality was increased and survival time shortened in force fed animals. These observations suggest that anorexia, by reducing energy intake, has a significant role in the early defense of the host.

Original languageEnglish (US)
Pages (from-to)593-596
Number of pages4
JournalAmerican Journal of Clinical Nutrition
Volume32
Issue number3
DOIs
StatePublished - 1979

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