Animal Models to Study the Biology of Amyloid-β Protein Misfolding in Alzheimer Disease

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationProtein Misfolding Diseases
Subtitle of host publicationCurrent and Emerging Principles and Therapies
PublisherJohn Wiley and Sons
Number of pages17
ISBN (Print)9780471799283
StatePublished - Jul 2 2010


  • 56 and memory loss and differentiating between - roles of Aβ and amyloid plaques in memory loss
  • Animal models, studying biology of amyloid-β protein misfolding in Alzheimer disease
  • Evidence in mice and humans - supporting hypothesis that Aβ initiates brain dysfunction, ABD Aβ and TAU, mediating brain degeneration

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