Angiosarcoma of the prostate gland following brachytherapy for prostatic adenocarcinoma

Arjun Gupta, Mrinal M. Patnaik, Harris V. Naina

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Prostatic adenocarcinoma is the most common cancer in men, but only a handful of cases of prostatic angiosarcoma have been reported in the literature. Prior radiation therapy for prostatic adenocarcinoma has been hypothesized to be a risk factor for angiosarcoma. The increasing practice of prostate cancer screening and the use of radiation therapy for management of prostatic adenocarcinoma will likely lead to more cases of prostatic angiosarcoma. Diagnosis is made by tissue sampling. Optimal management of these aggressive tumors remains to be defined and outcomes are poor with a high 1-year mortality. Primary care physicians and urologists should be aware of this rare entity and refer these patients to specialist centers where they can be managed by a multidisciplinary team. We report a case of angiosarcoma of the prostate gland diagnosed in a male presenting with lower urinary tract symptoms 5 years after brachytherapy for prostate adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)109-112
Number of pages4
JournalCurrent Urology
Issue number2
StatePublished - Aug 20 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
Copyright © 2014 S. Karger AG, Basel.


  • Prostate biopsy
  • Prostate cancer
  • Radiation-induced cancer
  • Sarcoma


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