Abstract
Angiogenesis inhibition with bevacizumab and other agents of this class are showing significant activity in a variety of cancers. In prostate cancer, the single agent activity has been low, but the addition of these agents to chemotherapy may be the area in which they provide their greatest clinical benefit. An ongoing study conducted by the Cancer and Leukemia Group B will test this approach in men with metastatic hormone refractory prostate cancer. Future studies may test the efficacy of anti-angiogenic strategies in earlier stage disease as well as in combination with other approaches. This review will highlight the clinical experience to date with angiogenesis inhibitors in prostate cancer and the ongoing studies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 250-253 |
| Number of pages | 4 |
| Journal | Urologic Oncology: Seminars and Original Investigations |
| Volume | 24 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 2006 |
| Externally published | Yes |
Bibliographical note
Copyright:Copyright 2008 Elsevier B.V., All rights reserved.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Angiogenesis inhibitors
- Bevacizumab
- Hormone refractory prostate cancer
- Prostate cancer
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