Anatomy and physiology overview of the cardiac conduction system

Timothy G Laske, Paul A. Iaizzo

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The intrinsic conduction system of the heart is comprised of several specialized subpopulations of cells that either spontaneously generate electrical activity (pacemaker cells) or preferentially conduct this activity throughout the chambers in a coordinated fashion. This chapter will discuss the details of what we know today about the conduction system and put such discoveries into a historical context. The cardiac action potential underlies signaling within the heart, and the various populations of myocytes elicit signature waveforms. The recording or active sensing of these potentials is important in both research and clinical arenas. This chapter aims to present a basic understanding of the cardiac conduction system to provide the reader with a foundation for future research and reading on this topic. The information in this chapter is not comprehensive and should not be used to make decisions related to patient care.

Original languageEnglish (US)
Title of host publicationCardiac Electrophysiology Methods and Models
Subtitle of host publicationA Practical Handbook for Scientists, Engineers, and Clinicians
PublisherSpringer Nature
Pages89-118
Number of pages30
ISBN (Electronic)9783031710674
ISBN (Print)9783031710667
DOIs
StatePublished - Dec 24 2024

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2010, 2024. All rights reserved.

Keywords

  • Atrioventricular node
  • Cardiac action potential
  • Cardiac conduction
  • Depolarization
  • Electrophysiology
  • Gap junction
  • Sinoatrial node

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