This article reviews the recent developments in nonaqueous capillary electrophoresis and discusses the effect of the solvent on analyte-additive interactions. When nonaqueous solvents are used, solvophobic interactions are generally weaker than those in water; therefore, those additives that can change the analyte mobility through electrostatic or donor-acceptor interactions should be further explored.
- Cohesion energy density
- Dielectric constant
- Electron donor-acceptor interaction
- Nonaqueous capillary electrophoresis
- Solvent effect