Analysis of a malondialdehyde-deoxyguanosine adduct in human leukocyte DNA by liquid chromatography nanoelectrospray-high-resolution tandem mass spectrometry

Keyphrases

• Leukocytes 100%
• Liquid Chromatography 100%
• Malondialdehyde 100%
• 2′-Deoxyguanosine 100%
• Leukocyte DNA 100%
• M1dG 100%
• Nanoelectrospray 100%
• High-resolution Tandem Mass Spectrometry 100%
• Nanospray Desorption Electrospray Ionization (nano-DESI) 33%
• Highly Sensitive 16%
• Inflammation 16%
• Human Subjects 16%
• Cardiovascular Disease 16%
• DNA Adducts 16%
• Human Disease 16%
• Lipid Peroxidation 16%
• Neurodegenerative Diseases 16%
• Pathophysiological Roles 16%
• Limit of Quantification 16%
• Physiological Condition 16%
• Prostaglandins 16%
• Sodium Borohydride 16%
• Solid-phase Extraction 16%
• Hydrolysate 16%
• Amol 16%
• Tandem Mass Spectrometry 16%
• Enzymatic Hydrolysis 16%
• Column Chromatography 16%
• Form-stable 16%
• Pyrimido 16%
• DNA Hydrolysis 16%
• Extraction Chromatography 16%
• Method Accuracy 16%
• Am(III) 16%
• Method Precision 16%
• Energy-resolved Collision-induced Dissociation (ER-CID) 16%
• Limit of Detection 16%
• MS Method 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Malonaldehyde 100%
• Deoxyguanosine 100%
• Disease 66%
• Malignant Neoplasm 33%
• Human 33%
• Sodium Borohydride 33%
• Inflammation 33%
• Prostaglandin 33%
• Degenerative Disease 33%
• Purine 33%
• Cardiovascular Disease 33%

Chemistry

• Deoxyribonucleic Acid 100%
• Liquid Chromatography 100%
• Tandem Mass Spectrometry 100%
• High Resolution Mass Spectrometry (HRMS) 33%
• Sodium Borohydride 11%
• Solid-Phase Extraction 11%
• Collisional 11%
• Genotoxic 11%
• Column Chromatography 11%
• Enzymatic Hydrolysis 11%
• peroxidation 11%
• Prostaglandin 11%