Anal Intraepithelial Neoplasia

Wolfgang B. Gaertner; Mukta K. Krane

doi:10.1007/978-3-030-66049-9_19

Anal Intraepithelial Neoplasia

Wolfgang B. Gaertner
, Mukta K. Krane

Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Anal intraepithelial neoplasia (AIN) is a dysplastic condition of squamous tissue caused by the human papilloma virus (HPV) and is generally considered to be a premalignant stage of anal cancer. Most patients with this condition are asymptomatic but require risk stratification in order to structure prevention strategies, screening, treatment, and surveillance. While there is no definitive consensus on treatment guidelines, a general approach of targeted ablation for high-risk lesions in immunocompetent patients and a combination of close observation, topical agents, and focused ablation in patients with low-grade dysplasia or immunocompromised patients are accepted.

Original language	English (US)
Title of host publication	The ASCRS Textbook of Colon and Rectal Surgery
Subtitle of host publication	Fourth Edition
Publisher	Springer International Publishing
Pages	343-354
Number of pages	12
ISBN (Electronic)	9783030660499
ISBN (Print)	9783030660482
DOIs	https://doi.org/10.1007/978-3-030-66049-9_19
State	Published - Jan 1 2021

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2022.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Anal cancer
Anal intraepithelial neoplasia
Dysplasia
Human papilloma virus

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10.1007/978-3-030-66049-9_19

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title = "Anal Intraepithelial Neoplasia",

abstract = "Anal intraepithelial neoplasia (AIN) is a dysplastic condition of squamous tissue caused by the human papilloma virus (HPV) and is generally considered to be a premalignant stage of anal cancer. Most patients with this condition are asymptomatic but require risk stratification in order to structure prevention strategies, screening, treatment, and surveillance. While there is no definitive consensus on treatment guidelines, a general approach of targeted ablation for high-risk lesions in immunocompetent patients and a combination of close observation, topical agents, and focused ablation in patients with low-grade dysplasia or immunocompromised patients are accepted.",

keywords = "Anal cancer, Anal intraepithelial neoplasia, Dysplasia, Human papilloma virus",

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doi = "10.1007/978-3-030-66049-9\_19",

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AU - Gaertner, Wolfgang B.

AU - Krane, Mukta K.

N1 - Publisher Copyright: © Springer Nature Switzerland AG 2022.

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Anal intraepithelial neoplasia (AIN) is a dysplastic condition of squamous tissue caused by the human papilloma virus (HPV) and is generally considered to be a premalignant stage of anal cancer. Most patients with this condition are asymptomatic but require risk stratification in order to structure prevention strategies, screening, treatment, and surveillance. While there is no definitive consensus on treatment guidelines, a general approach of targeted ablation for high-risk lesions in immunocompetent patients and a combination of close observation, topical agents, and focused ablation in patients with low-grade dysplasia or immunocompromised patients are accepted.

AB - Anal intraepithelial neoplasia (AIN) is a dysplastic condition of squamous tissue caused by the human papilloma virus (HPV) and is generally considered to be a premalignant stage of anal cancer. Most patients with this condition are asymptomatic but require risk stratification in order to structure prevention strategies, screening, treatment, and surveillance. While there is no definitive consensus on treatment guidelines, a general approach of targeted ablation for high-risk lesions in immunocompetent patients and a combination of close observation, topical agents, and focused ablation in patients with low-grade dysplasia or immunocompromised patients are accepted.

KW - Anal cancer

KW - Anal intraepithelial neoplasia

KW - Dysplasia

KW - Human papilloma virus

UR - https://www.scopus.com/pages/publications/85170178501

UR - https://www.scopus.com/pages/publications/85170178501#tab=citedBy

U2 - 10.1007/978-3-030-66049-9_19

DO - 10.1007/978-3-030-66049-9_19

M3 - Chapter

AN - SCOPUS:85170178501

SN - 9783030660482

SP - 343

EP - 354

BT - The ASCRS Textbook of Colon and Rectal Surgery

PB - Springer International Publishing

ER -

Anal Intraepithelial Neoplasia

Abstract

Bibliographical note

UN SDGs

Keywords

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