Anal Intraepithelial Neoplasia

Wolfgang B. Gaertner; Mukta K. Krane

doi:10.1007/978-3-030-66049-9_19

Anal Intraepithelial Neoplasia

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Anal intraepithelial neoplasia (AIN) is a dysplastic condition of squamous tissue caused by the human papilloma virus (HPV) and is generally considered to be a premalignant stage of anal cancer. Most patients with this condition are asymptomatic but require risk stratification in order to structure prevention strategies, screening, treatment, and surveillance. While there is no definitive consensus on treatment guidelines, a general approach of targeted ablation for high-risk lesions in immunocompetent patients and a combination of close observation, topical agents, and focused ablation in patients with low-grade dysplasia or immunocompromised patients are accepted.

Original language	English (US)
Title of host publication	The ASCRS Textbook of Colon and Rectal Surgery
Subtitle of host publication	Fourth Edition
Publisher	Springer International Publishing
Pages	343-354
Number of pages	12
ISBN (Electronic)	9783030660499
ISBN (Print)	9783030660482
DOIs	https://doi.org/10.1007/978-3-030-66049-9_19
State	Published - Jan 1 2021

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2022.

Keywords

Anal cancer
Anal intraepithelial neoplasia
Dysplasia
Human papilloma virus

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-3-030-66049-9_19

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AU - Krane, Mukta K.

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N2 - Anal intraepithelial neoplasia (AIN) is a dysplastic condition of squamous tissue caused by the human papilloma virus (HPV) and is generally considered to be a premalignant stage of anal cancer. Most patients with this condition are asymptomatic but require risk stratification in order to structure prevention strategies, screening, treatment, and surveillance. While there is no definitive consensus on treatment guidelines, a general approach of targeted ablation for high-risk lesions in immunocompetent patients and a combination of close observation, topical agents, and focused ablation in patients with low-grade dysplasia or immunocompromised patients are accepted.

AB - Anal intraepithelial neoplasia (AIN) is a dysplastic condition of squamous tissue caused by the human papilloma virus (HPV) and is generally considered to be a premalignant stage of anal cancer. Most patients with this condition are asymptomatic but require risk stratification in order to structure prevention strategies, screening, treatment, and surveillance. While there is no definitive consensus on treatment guidelines, a general approach of targeted ablation for high-risk lesions in immunocompetent patients and a combination of close observation, topical agents, and focused ablation in patients with low-grade dysplasia or immunocompromised patients are accepted.

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KW - Dysplasia

KW - Human papilloma virus

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ER -

Anal Intraepithelial Neoplasia

Abstract

Bibliographical note

Keywords

UN SDGs

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