An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline

Siva Kumar Talluri; Arumugam Sudalai

doi:10.1016/j.tet.2007.07.012

An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline

Siva Kumar Talluri
, Arumugam Sudalai

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step.

Original language	English (US)
Pages (from-to)	9758-9763
Number of pages	6
Journal	Tetrahedron
Volume	63
Issue number	39
DOIs	https://doi.org/10.1016/j.tet.2007.07.012
State	Published - Sep 24 2007

Bibliographical note

Funding Information:
S.K.T. thanks CSIR, New Delhi, for financial support. The authors thank Dr. B. D. Kulkarni, Head, CE-PD Division, for his constant encouragement and support.

Keywords

Asymmetric reactions
Organocatalysis
Proline
α-Amination
α-Aminooxylation

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10.1016/j.tet.2007.07.012

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title = "An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline",

abstract = "An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step.",

keywords = "Asymmetric reactions, Organocatalysis, Proline, α-Amination, α-Aminooxylation",

author = "Talluri, \{Siva Kumar\} and Arumugam Sudalai",

note = "Funding Information: S.K.T. thanks CSIR, New Delhi, for financial support. The authors thank Dr. B. D. Kulkarni, Head, CE-PD Division, for his constant encouragement and support.",

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AU - Talluri, Siva Kumar

AU - Sudalai, Arumugam

N1 - Funding Information: S.K.T. thanks CSIR, New Delhi, for financial support. The authors thank Dr. B. D. Kulkarni, Head, CE-PD Division, for his constant encouragement and support.

PY - 2007/9/24

Y1 - 2007/9/24

N2 - An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step.

AB - An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step.

KW - Asymmetric reactions

KW - Organocatalysis

KW - Proline

KW - α-Amination

KW - α-Aminooxylation

UR - https://www.scopus.com/pages/publications/34547738969

UR - https://www.scopus.com/pages/publications/34547738969#tab=citedBy

U2 - 10.1016/j.tet.2007.07.012

DO - 10.1016/j.tet.2007.07.012

M3 - Article

AN - SCOPUS:34547738969

SN - 0040-4020

VL - 63

SP - 9758

EP - 9763

JO - Tetrahedron

JF - Tetrahedron

IS - 39

ER -

An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline

Abstract

Bibliographical note

Keywords

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