L-Cysteine-glutathione mixed disulfide (CySSG), a prodrug of glutathione (GSH), was found to be orally bioavailable in mice, and protected mice against a toxic dose of acetaminophen. If oral bioavailability can also be demonstrated in humans, a wide range of applicability for CySSG can be envisioned.
|Original language||English (US)|
|State||Published - Jun 2021|
Bibliographical noteFunding Information:
Funding: This research was funded by the Dept of Veterans Affairs, Minneapolis, MN, and the Center for Drug Design, University of Minnesota.
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PubMed: MeSH publication types
- Journal Article