An iron-sulfur cluster loop motif in the archaeoglobus fulgidus uracil-DNA glycosylase mediates efficient uracil recognition and removal

Keyphrases

• Uracil 100%
• Iron-sulfur Cluster 100%
• Uracil-DNA Glycosylase 100%
• Archaeoglobus Fulgidus 100%
• Excision 85%
• Single-stranded DNA (ssDNA) 42%
• Cysteine 28%
• Extrusion 14%
• Positively Charged 14%
• Thiolate 14%
• Ligation 14%
• Helix 14%
• DNA Binding 14%
• Duplex 14%
• Loop Conformation 14%
• Loop Flexibility 14%
• Charged Residue 14%
• Base Excision Repair 14%
• Reducing Activity 14%
• Hyperthermophilic 14%
• DNA Context 14%
• Duplex DNA 14%
• Uracil in DNA 14%
• Glycoside Hydrolase 14%
• DNA Damage Recognition 14%
• MutY 14%
• Endonuclease III 14%
• DNA Catalysis 14%
• Efficient Recognition 14%
• Base Excision Repair Pathway 14%

Biochemistry, Genetics and Molecular Biology

• Iron-Sulfur Cluster 100%
• Archaeoglobus fulgidus 100%
• Uracil-DNA Glycosylase 100%
• Uracil 100%
• Base Excision Repair 25%
• Arginine 25%
• Cysteine 25%
• Alanine 25%
• Conformation 12%
• Thiolates 12%
• Glycosylase 12%
• Endonuclease 12%
• DNA Damage 12%
• DNA Binding 12%