TY - JOUR
T1 - An Improved Oil Emulsion Synthesis Method for Large, Porous Zirconia Particles for Packed- or Fluidized-Bed Protein Chromatography
AU - Robichaud, Michael J.
AU - Sathyagal, Arun N.
AU - Carr, Peter W.
AU - McCormick, Alon V.
AU - Flickinger, Michael C.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1997
Y1 - 1997
N2 - A previously reported oil emulsion technique for the synthesis of large, porous zirconia particles has been modified to overcome problems of nonreproducibility, formation of non-spherical or broken particles, and low yield of chromatographically useful particles. The improved technique described here uses a concentrated sol and an in-line mixer to successfully solve these problems. The results indicate that the stirring rate used to maintain the emulsion during drying has a strong effect on the final particle size.
AB - A previously reported oil emulsion technique for the synthesis of large, porous zirconia particles has been modified to overcome problems of nonreproducibility, formation of non-spherical or broken particles, and low yield of chromatographically useful particles. The improved technique described here uses a concentrated sol and an in-line mixer to successfully solve these problems. The results indicate that the stirring rate used to maintain the emulsion during drying has a strong effect on the final particle size.
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U2 - 10.1080/01496399708000785
DO - 10.1080/01496399708000785
M3 - Article
AN - SCOPUS:0031251978
SN - 0149-6395
VL - 32
SP - 2547
EP - 2559
JO - Separation Science and Technology
JF - Separation Science and Technology
IS - 15
ER -