An improved assay for cyclic GMP using an insect binding protein

Ann Marie Fallon, G. R. Wyatt

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Protein from silkmoth pupal fat body was used to develop a simple radioisotope-competition binding assay for cGMP, with increased sensitivity and specificity over the currently used protein binding assay (2). With this assay, we have initiated a study of the distribution of cGMP in crickets, which contain unusually high levels, as previously reported by Ishikawa et al. (11).

Original languageEnglish (US)
Pages (from-to)614-619
Number of pages6
JournalAnalytical Biochemistry
Issue number2
StatePublished - Feb 1975
Externally publishedYes

Bibliographical note

Funding Information:
’ This work was supported by Grants from the National Research Council of Canada (A6954) and the National Institutes of Health, U.S. Public Health Service (HD-07951).


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