Fritz-Laylin et al. (2017. J. Cell Biol. https ://doi .org /10 .1083 /jcb .201701074) take advantage of the deep knowledge of mechanisms of actin-based motility and a growing number of sequenced genomes across the tree of life to gain insight into the machinery needed for pseudopod-based amoeboid motility and how it evolved.
Bibliographical noteFunding Information:
Work in the authors' laboratories is supported by grants from the American Heart Association (16GRNT31150007) and the University of Minnesota Medical Foundation to M.A. Titus and from the National Science Foundation (MCB-1244593) to H.V. Goodson. The authors declare no competing financial interests.
© 2017 Titus and Goodson.