An endocrine perspective on menstrual suppression for adolescents: Achieving good suppression while optimizing bone health

Amit Lahoti, Christine Yu, Preneet Cheema Brar, Austin Dalgo, Evgenia Gourgari, Rebecca Harris, Manmohan K. Kamboj, Seth Marks, Radha Nandagopal, Laura Page, Vandana Raman, Danielle G. Reynolds, Kyriakie Sarafoglou, Carrie Terrell, Takara L. Stanley

Research output: Contribution to journalReview articlepeer-review

Abstract

Suppression of menstruation and/or ovarian function in adolescent girls may be desired for a variety of reasons. Numerous medical options exist. The choice of the appropriate modality for an individual patient depends on several factors based on differences in the efficacy of achieving menstrual suppression as well as in their side effect profiles. Adolescence is also a period of bone mass accrual in girls, and several of these modalities may negatively influence peak bone mass. This review focuses on the efficacy of achieving menstrual suppression and the effect on bone health of the various options through an overview of the current literature and also highlights areas in need of further research.

Original languageEnglish (US)
Pages (from-to)1355-1369
Number of pages15
JournalJournal of Pediatric Endocrinology and Metabolism
Volume34
Issue number11
Early online dateAug 12 2021
DOIs
StatePublished - Nov 25 2021

Bibliographical note

Publisher Copyright:
© 2021 Walter de Gruyter GmbH, Berlin/Boston.

Keywords

  • adolescents
  • amenorrhea
  • bone health
  • contraception
  • ethics
  • menstrual suppression
  • osteoporosis

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