An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children

C. E. Krafft; J. E. Pierce; N. F. Schwarz; L. Chi; A. L. Weinberger; D. J. Schaeffer; A. L. Rodrigue; J. Camchong; J. D. Allison; N. E. Yanasak; T. Liu; C. L. Davis; J. E. McDowell

doi:10.1016/j.neuroscience.2013.09.052

An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children

C. E. Krafft, J. E. Pierce, N. F. Schwarz, L. Chi, A. L. Weinberger, D. J. Schaeffer, A. L. Rodrigue, J. Camchong, J. D. Allison, N. E. Yanasak, T. Liu, C. L. Davis, J. E. McDowell

Psychiatry & Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Children with low aerobic fitness have altered brain function compared to higher-fit children. This study examined the effect of an 8-month exercise intervention on resting state synchrony. Twenty-two sedentary, overweight (body mass index ≥85th percentile) children 8-11. years old were randomly assigned to one of two after-school programs: aerobic exercise (n= 13) or sedentary attention control (n= 9). Before and after the 8-month programs, all subjects participated in resting state functional magnetic resonance imaging scans. Independent components analysis identified several networks, with four chosen for between-group analysis: salience, default mode, cognitive control, and motor networks. The default mode, cognitive control, and motor networks showed more spatial refinement over time in the exercise group compared to controls. The motor network showed increased synchrony in the exercise group with the right medial frontal gyrus compared to controls. Exercise behavior may enhance brain development in children.

Original language	English (US)
Pages (from-to)	445-455
Number of pages	11
Journal	Neuroscience
Volume	256
DOIs	https://doi.org/10.1016/j.neuroscience.2013.09.052
State	Published - Jan 3 2014

Bibliographical note

Funding Information:
The project described was supported by the National Institutes of Health ( R01 HL087923 and HL087923-03S2 ) and the National Science Foundation Graduate Research Fellowship Program .

Keywords

Aerobic exercise
Cognitive control
Default mode
Development
Obesity
Resting state fMRI

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1016/j.neuroscience.2013.09.052

Find It

Find It at U of M Libraries

Cite this

Krafft, C. E., Pierce, J. E., Schwarz, N. F., Chi, L., Weinberger, A. L., Schaeffer, D. J., Rodrigue, A. L., Camchong, J., Allison, J. D., Yanasak, N. E., Liu, T., Davis, C. L., & McDowell, J. E. (2014). An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children. Neuroscience, 256, 445-455. https://doi.org/10.1016/j.neuroscience.2013.09.052

Krafft, CE, Pierce, JE, Schwarz, NF, Chi, L, Weinberger, AL, Schaeffer, DJ, Rodrigue, AL, Camchong, J, Allison, JD, Yanasak, NE, Liu, T, Davis, CL & McDowell, JE 2014, 'An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children', Neuroscience, vol. 256, pp. 445-455. https://doi.org/10.1016/j.neuroscience.2013.09.052

@article{a7de4ca8b13d42caac0d3328785507d4,

title = "An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children",

abstract = "Children with low aerobic fitness have altered brain function compared to higher-fit children. This study examined the effect of an 8-month exercise intervention on resting state synchrony. Twenty-two sedentary, overweight (body mass index ≥85th percentile) children 8-11. years old were randomly assigned to one of two after-school programs: aerobic exercise (n= 13) or sedentary attention control (n= 9). Before and after the 8-month programs, all subjects participated in resting state functional magnetic resonance imaging scans. Independent components analysis identified several networks, with four chosen for between-group analysis: salience, default mode, cognitive control, and motor networks. The default mode, cognitive control, and motor networks showed more spatial refinement over time in the exercise group compared to controls. The motor network showed increased synchrony in the exercise group with the right medial frontal gyrus compared to controls. Exercise behavior may enhance brain development in children.",

keywords = "Aerobic exercise, Cognitive control, Default mode, Development, Obesity, Resting state fMRI",

author = "Krafft, {C. E.} and Pierce, {J. E.} and Schwarz, {N. F.} and L. Chi and Weinberger, {A. L.} and Schaeffer, {D. J.} and Rodrigue, {A. L.} and J. Camchong and Allison, {J. D.} and Yanasak, {N. E.} and T. Liu and Davis, {C. L.} and McDowell, {J. E.}",

note = "Funding Information: The project described was supported by the National Institutes of Health ( R01 HL087923 and HL087923-03S2 ) and the National Science Foundation Graduate Research Fellowship Program .",

year = "2014",

month = jan,

day = "3",

doi = "10.1016/j.neuroscience.2013.09.052",

language = "English (US)",

volume = "256",

pages = "445--455",

journal = "Neuroscience",

issn = "0306-4522",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children

AU - Krafft, C. E.

AU - Pierce, J. E.

AU - Schwarz, N. F.

AU - Chi, L.

AU - Weinberger, A. L.

AU - Schaeffer, D. J.

AU - Rodrigue, A. L.

AU - Camchong, J.

AU - Allison, J. D.

AU - Yanasak, N. E.

AU - Liu, T.

AU - Davis, C. L.

AU - McDowell, J. E.

N1 - Funding Information: The project described was supported by the National Institutes of Health ( R01 HL087923 and HL087923-03S2 ) and the National Science Foundation Graduate Research Fellowship Program .

PY - 2014/1/3

Y1 - 2014/1/3

N2 - Children with low aerobic fitness have altered brain function compared to higher-fit children. This study examined the effect of an 8-month exercise intervention on resting state synchrony. Twenty-two sedentary, overweight (body mass index ≥85th percentile) children 8-11. years old were randomly assigned to one of two after-school programs: aerobic exercise (n= 13) or sedentary attention control (n= 9). Before and after the 8-month programs, all subjects participated in resting state functional magnetic resonance imaging scans. Independent components analysis identified several networks, with four chosen for between-group analysis: salience, default mode, cognitive control, and motor networks. The default mode, cognitive control, and motor networks showed more spatial refinement over time in the exercise group compared to controls. The motor network showed increased synchrony in the exercise group with the right medial frontal gyrus compared to controls. Exercise behavior may enhance brain development in children.

AB - Children with low aerobic fitness have altered brain function compared to higher-fit children. This study examined the effect of an 8-month exercise intervention on resting state synchrony. Twenty-two sedentary, overweight (body mass index ≥85th percentile) children 8-11. years old were randomly assigned to one of two after-school programs: aerobic exercise (n= 13) or sedentary attention control (n= 9). Before and after the 8-month programs, all subjects participated in resting state functional magnetic resonance imaging scans. Independent components analysis identified several networks, with four chosen for between-group analysis: salience, default mode, cognitive control, and motor networks. The default mode, cognitive control, and motor networks showed more spatial refinement over time in the exercise group compared to controls. The motor network showed increased synchrony in the exercise group with the right medial frontal gyrus compared to controls. Exercise behavior may enhance brain development in children.

KW - Aerobic exercise

KW - Cognitive control

KW - Default mode

KW - Development

KW - Obesity

KW - Resting state fMRI

UR - http://www.scopus.com/inward/record.url?scp=84889573616&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889573616&partnerID=8YFLogxK

U2 - 10.1016/j.neuroscience.2013.09.052

DO - 10.1016/j.neuroscience.2013.09.052

M3 - Article

C2 - 24096138

AN - SCOPUS:84889573616

SN - 0306-4522

VL - 256

SP - 445

EP - 455

JO - Neuroscience

JF - Neuroscience

ER -

An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children

Abstract

Bibliographical note

Keywords

UN SDGs

Publisher link

Find It

Other files and links

Fingerprint

Cite this