An efficient synthesis of 1,8-dioxo-octahydro-xanthene derivatives promoted by a room temperature ionic liquid at ambient conditions under ultrasound irradiation

K. Venkatesan, Suresh S. Pujari, R. J. Lahoti, K. V. Srinivasan

Research output: Contribution to journalArticle

102 Scopus citations

Abstract

The condensation reaction involving an aldehyde and diketone was efficiently promoted by the Ionic liquid, [Hbim]BF4 (IL) as a reaction medium with methanol as co-solvent at ambient temperature under ultrasonic irradiation to afford the corresponding 1,8-dioxo-octahydroxanthene (xanthene) derivatives in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under ambient temperature without the requirement of any added catalyst. The reaction times and yields are compared with p-TSA catalyzed synthesis of xanthenes under thermal conditions, which is also reported for the first time under our reaction conditions.

Original languageEnglish (US)
Pages (from-to)548-553
Number of pages6
JournalUltrasonics Sonochemistry
Volume15
Issue number4
DOIs
StatePublished - Apr 2008

Keywords

  • Aldehydes
  • Ambient conditions
  • Brønsted acidity
  • Dimedone
  • Ionic liquid
  • Ultrasound
  • Xanthenes

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