An efficient solid-phase synthesis of 3-carboxycoumarins based on a scaffold-polymerbound cyclic malonic ester

Jing Tang; Xian Huang

doi:10.3184/030823403103174092

An efficient solid-phase synthesis of 3-carboxycoumarins based on a scaffold-polymerbound cyclic malonic ester

Jing Tang
, Xian Huang

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The condensation of substituted o-methoxybenzaldehydes or o-hydroxybenzaldehydes with a resin-bound cyclic malonic ester 3 afforded the resin 4 without catalyst. Cyclisation of the resin 4 in sulfuric acid formed 3-carboxycoumarins in good yield and excellent purity.

Original language	English (US)
Pages (from-to)	354-355
Number of pages	2
Journal	Journal of Chemical Research - Part S
Issue number	6
DOIs	https://doi.org/10.3184/030823403103174092
State	Published - Jun 1 2003
Externally published	Yes

Keywords

3-carboxycoumarins
O-methoxybenzaldehydes or o-hydroxybenzaldehydes
Resin-bound cyclic malonic acid ester

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10.3184/030823403103174092

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title = "An efficient solid-phase synthesis of 3-carboxycoumarins based on a scaffold-polymerbound cyclic malonic ester",

abstract = "The condensation of substituted o-methoxybenzaldehydes or o-hydroxybenzaldehydes with a resin-bound cyclic malonic ester 3 afforded the resin 4 without catalyst. Cyclisation of the resin 4 in sulfuric acid formed 3-carboxycoumarins in good yield and excellent purity.",

keywords = "3-carboxycoumarins, O-methoxybenzaldehydes or o-hydroxybenzaldehydes, Resin-bound cyclic malonic acid ester",

author = "Jing Tang and Xian Huang",

year = "2003",

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day = "1",

doi = "10.3184/030823403103174092",

language = "English (US)",

pages = "354--355",

journal = "Journal of Chemical Research - Part S",

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publisher = "Scientific Reviews 2000 Ltd.",

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T1 - An efficient solid-phase synthesis of 3-carboxycoumarins based on a scaffold-polymerbound cyclic malonic ester

AU - Tang, Jing

AU - Huang, Xian

PY - 2003/6/1

Y1 - 2003/6/1

N2 - The condensation of substituted o-methoxybenzaldehydes or o-hydroxybenzaldehydes with a resin-bound cyclic malonic ester 3 afforded the resin 4 without catalyst. Cyclisation of the resin 4 in sulfuric acid formed 3-carboxycoumarins in good yield and excellent purity.

AB - The condensation of substituted o-methoxybenzaldehydes or o-hydroxybenzaldehydes with a resin-bound cyclic malonic ester 3 afforded the resin 4 without catalyst. Cyclisation of the resin 4 in sulfuric acid formed 3-carboxycoumarins in good yield and excellent purity.

KW - 3-carboxycoumarins

KW - O-methoxybenzaldehydes or o-hydroxybenzaldehydes

KW - Resin-bound cyclic malonic acid ester

UR - https://www.scopus.com/pages/publications/0141456248

UR - https://www.scopus.com/pages/publications/0141456248#tab=citedBy

U2 - 10.3184/030823403103174092

DO - 10.3184/030823403103174092

M3 - Article

AN - SCOPUS:0141456248

SN - 0308-2342

SP - 354

EP - 355

JO - Journal of Chemical Research - Part S

JF - Journal of Chemical Research - Part S

IS - 6

ER -

An efficient solid-phase synthesis of 3-carboxycoumarins based on a scaffold-polymerbound cyclic malonic ester

Abstract

Keywords

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