An efficient method for the preparation of peptide alcohols

Alan Roy Katritzky; Nader Elmaghwry Abo-Dya; Srinivasa Rao Tala; Kapil Gyanda; Zakaria Kamel Abdel-Samii

doi:10.1039/b905730g

An efficient method for the preparation of peptide alcohols

Alan Roy Katritzky
, Nader Elmaghwry Abo-Dya
, Srinivasa Rao Tala
, Kapil Gyanda
, Zakaria Kamel Abdel-Samii

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

N-Protected ll-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d′) and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(α-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a′) and N-protected(α-dipeptidoyl)benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.

Original language	English (US)
Pages (from-to)	4444-4447
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	7
Issue number	21
DOIs	https://doi.org/10.1039/b905730g
State	Published - 2009
Externally published	Yes

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10.1039/b905730g

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title = "An efficient method for the preparation of peptide alcohols",

abstract = "N-Protected ll-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d′) and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(α-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a′) and N-protected(α-dipeptidoyl)benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.",

author = "Katritzky, \{Alan Roy\} and Abo-Dya, \{Nader Elmaghwry\} and Tala, \{Srinivasa Rao\} and Kapil Gyanda and Abdel-Samii, \{Zakaria Kamel\}",

year = "2009",

doi = "10.1039/b905730g",

language = "English (US)",

volume = "7",

pages = "4444--4447",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

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T1 - An efficient method for the preparation of peptide alcohols

AU - Katritzky, Alan Roy

AU - Abo-Dya, Nader Elmaghwry

AU - Tala, Srinivasa Rao

AU - Gyanda, Kapil

AU - Abdel-Samii, Zakaria Kamel

PY - 2009

Y1 - 2009

N2 - N-Protected ll-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d′) and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(α-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a′) and N-protected(α-dipeptidoyl)benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.

AB - N-Protected ll-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d′) and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(α-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a′) and N-protected(α-dipeptidoyl)benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.

UR - https://www.scopus.com/pages/publications/70350007193

UR - https://www.scopus.com/pages/publications/70350007193#tab=citedBy

U2 - 10.1039/b905730g

DO - 10.1039/b905730g

M3 - Article

C2 - 19830293

AN - SCOPUS:70350007193

SN - 1477-0520

VL - 7

SP - 4444

EP - 4447

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 21

ER -

An efficient method for the preparation of peptide alcohols

Abstract

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