An efficient method for the preparation of peptide alcohols

Alan Roy Katritzky, Nader Elmaghwry Abo-Dya, Srinivasa Rao Tala, Kapil Gyanda, Zakaria Kamel Abdel-Samii

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

N-Protected ll-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d′) and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(α-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a′) and N-protected(α-dipeptidoyl)benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.

Original languageEnglish (US)
Pages (from-to)4444-4447
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume7
Issue number21
DOIs
StatePublished - Oct 21 2009

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