An efficient boric acid-mediated preparation of α-hydroxyamides

J. Sravan Kumar, Subash C. Jonnalagadda, Venkatram R. Mereddy

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51 Scopus citations


An efficient methodology for the preparation of α-hydroxyamides via boric acid-mediated addition of isonitriles onto aldehydes has been developed. The reaction of isonitriles with α-boronobenzaldehyde takes place under intramolecular catalysis conditions to provide functionalized benzoxaboroles.

Original languageEnglish (US)
Pages (from-to)779-782
Number of pages4
JournalTetrahedron Letters
Issue number5
StatePublished - Feb 3 2010


  • Benzoxaboroles
  • Boric acid
  • Isonitriles
  • Multicomponent reactions


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