An atlas of mouse mammary gland development

M. M. Richert, K. L. Schwertfeger, J. W. Ryder, S. M. Anderson

Research output: Contribution to journalArticle

251 Citations (Scopus)

Abstract

The mouse mammary gland is a complex tissue, which is continually undergoing changes in structure and function. Embryonically, the gland begins with invasion of the underlying fat pad by a rudimentary ductal structure. Postnatal growth occurs in two phases: ductal growth and early alveolar development during estrous cycles, and cycles of proliferation, differentiation, and death that occur with each pregnancy, lactation, and involution. The variety of epithelial structures and stromal changes throughout the life of a mammary gland makes it a challenge to study. The purpose of this histological review is to give a brief representation of the morphological changes that occur throughout the cycle of mouse mammary gland development so that developmental changes observed in mouse models of mammary development can be appreciated.

Original languageEnglish (US)
Pages (from-to)227-241
Number of pages15
JournalJournal of mammary gland biology and neoplasia
Volume5
Issue number2
DOIs
StatePublished - Jan 1 2000

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Atlases
Human Mammary Glands
Estrous Cycle
Growth
Lactation
Adipose Tissue
Breast
Pregnancy

Keywords

  • Alveoli
  • Atlas
  • Duct
  • Mammary gland
  • Mouse

Cite this

An atlas of mouse mammary gland development. / Richert, M. M.; Schwertfeger, K. L.; Ryder, J. W.; Anderson, S. M.

In: Journal of mammary gland biology and neoplasia, Vol. 5, No. 2, 01.01.2000, p. 227-241.

Research output: Contribution to journalArticle

Richert, M. M. ; Schwertfeger, K. L. ; Ryder, J. W. ; Anderson, S. M. / An atlas of mouse mammary gland development. In: Journal of mammary gland biology and neoplasia. 2000 ; Vol. 5, No. 2. pp. 227-241.
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