An Assessment of Statin Safety by Nephrologists

Bert L Kasiske, Christoph Wanner, W. Charles O'Neill

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

Recently, concerns regarding potential adverse effects of the statins on the kidney have been raised. The Kidney Expert Panel of the National Lipid Association's (NLA) Safety Task Force, made up of 3 nephrologists, was convened to review all of the currently available evidence pertinent to determining whether statins cause kidney injury, independent of the known, rare mechanisms of rhabdomyolysis and allergic, drug-induced, interstitial nephritis. The Panel reviewed published and unpublished evidence and found none that suggested that statins, when used in doses currently approved by the US Food and Drug Administration (FDA), cause kidney injury.

Original languageEnglish (US)
JournalAmerican Journal of Cardiology
Volume97
Issue number8 SUPPL. 1
DOIs
StatePublished - Apr 17 2006

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