TY - JOUR
T1 - Amiodarone-induced alveolar haemorrhage
T2 - A rare complication of a common medication
AU - Tanawuttiwat, Tanyanan
AU - Harindhanavudhi, Tasma
AU - Hanif, Sara
AU - Sahloul, Mohammad Z.
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2010/7
Y1 - 2010/7
N2 - Amiodarone pulmonary toxicity (APT) is a common and distinctive form of drug-induced lung injury. Several patterns have been described and the most common pattern of APT is interstitial pneumonitis. However, amiodarone-induced diffused alveolar haemorrhage is rarely reported. We describe a case of early onset of APT manifested by respiratory distress, haemoptysis, severe hypoxia and bilateral pulmonary infiltrates that was finally diagnosed with amiodarone-induced diffuse alveolar haemorrhage. High suspicion of APT in patients with these non-specific clinical symptoms is needed. Early recognition and treatment are imperative.
AB - Amiodarone pulmonary toxicity (APT) is a common and distinctive form of drug-induced lung injury. Several patterns have been described and the most common pattern of APT is interstitial pneumonitis. However, amiodarone-induced diffused alveolar haemorrhage is rarely reported. We describe a case of early onset of APT manifested by respiratory distress, haemoptysis, severe hypoxia and bilateral pulmonary infiltrates that was finally diagnosed with amiodarone-induced diffuse alveolar haemorrhage. High suspicion of APT in patients with these non-specific clinical symptoms is needed. Early recognition and treatment are imperative.
KW - Alveolar haemorrhage
KW - Amiodarone
KW - Pulmonary toxicity
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U2 - 10.1016/j.hlc.2010.01.008
DO - 10.1016/j.hlc.2010.01.008
M3 - Article
C2 - 20356785
AN - SCOPUS:77953807966
SN - 1443-9506
VL - 19
SP - 435
EP - 437
JO - Heart Lung and Circulation
JF - Heart Lung and Circulation
IS - 7
ER -