Abstract
Amino acid analogs can inhibit several steps in the metabolism and/or utilization of the natural amino acids in mammalian cells. Mutants can be selected on the basis of their resistance to these analogs. Such mutants may be altered in their transport of amino acids, in the regulation of amino acid biosynthesis or in the utilization of amino acids for protein synthesis. Analysis of these mutants will help clarify the mechanisms which regulate these various processes.
Original language | English (US) |
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Pages (from-to) | 163-164 |
Number of pages | 2 |
Journal | Trends in Biochemical Sciences |
Volume | 8 |
Issue number | 5 |
DOIs | |
State | Published - May 1983 |
Externally published | Yes |