Amino acid analogs as tools for the study of amino acid metabolism in mammalian cells

Stuart M. Arfin, J. Stephen Gantt

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Amino acid analogs can inhibit several steps in the metabolism and/or utilization of the natural amino acids in mammalian cells. Mutants can be selected on the basis of their resistance to these analogs. Such mutants may be altered in their transport of amino acids, in the regulation of amino acid biosynthesis or in the utilization of amino acids for protein synthesis. Analysis of these mutants will help clarify the mechanisms which regulate these various processes.

Original languageEnglish (US)
Pages (from-to)163-164
Number of pages2
JournalTrends in Biochemical Sciences
Volume8
Issue number5
DOIs
StatePublished - May 1983
Externally publishedYes

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