Abstract
The lithium enolate derived from benzamidoacetone (1) can be regiospecifically alkylated at C(1) and stereospecifically added in conjugate fashion to cyclohexenone without resorting to protection of the free NH. Comparison is made with alkylations of methyl hippurate.
Original language | English (US) |
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Pages (from-to) | 3433-3436 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 26 |
Issue number | 29 |
DOIs | |
State | Published - 1985 |